You can schedule when a Tweakwise export needs to be executed within Magento. This is how it works.

​Navigate to Stores > Configuration > Catalog > Tweakwise > Export to find the settings. You'll see these options:

The Schedule field lets you fill in a 'formula' that determines when to execute an export. This is done using Cron. Check https://en.wikipedia.org/wiki/Cron to see how this works. If it doesn't seem to work for you, we can help you set up the Cron.